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Activation of JNK Signaling Mediates Connective Tissue Growth Factor Expression and Scar Formation in Corneal Wound Healing

Connective Tissue Growth Factor (CTGF) and Transforming growth factor-β1 (TGF-β1) are key growth factors in regulating corneal scarring. Although CTGF was induced by TGF-β1 and mediated many of fibroproliferative effects of TGF-β1, the signaling pathway for CTGF production in corneal scarring remain...

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Detalles Bibliográficos
Autores principales: Shi, Long, Chang, Yuan, Yang, Yongmei, Zhang, Ying, Yu, Fu-Shin X., Wu, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283717/
https://www.ncbi.nlm.nih.gov/pubmed/22363806
http://dx.doi.org/10.1371/journal.pone.0032128