Nonparametric Evaluation of Quantitative Traits in Population-Based Association Studies when the Genetic Model is Unknown

Statistical association between a single nucleotide polymorphism (SNP) genotype and a quantitative trait in genome-wide association studies is usually assessed using a linear regression model, or, in the case of non-normally distributed trait values, using the Kruskal-Wallis test. While linear regre...

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Detalles Bibliográficos
Autores principales: Konietschke, Frank, Libiger, Ondrej, Hothorn, Ludwig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283745/
https://www.ncbi.nlm.nih.gov/pubmed/22363593
http://dx.doi.org/10.1371/journal.pone.0031242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283745/
https://www.ncbi.nlm.nih.gov/pubmed/22363593
http://dx.doi.org/10.1371/journal.pone.0031242

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