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Nonparametric Evaluation of Quantitative Traits in Population-Based Association Studies when the Genetic Model is Unknown
Statistical association between a single nucleotide polymorphism (SNP) genotype and a quantitative trait in genome-wide association studies is usually assessed using a linear regression model, or, in the case of non-normally distributed trait values, using the Kruskal-Wallis test. While linear regre...
Autores principales: | Konietschke, Frank, Libiger, Ondrej, Hothorn, Ludwig A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283745/ https://www.ncbi.nlm.nih.gov/pubmed/22363593 http://dx.doi.org/10.1371/journal.pone.0031242 |
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