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Induction of ER Stress-Mediated Apoptosis by α-Lipoic Acid in A549 Cell Lines

BACKGROUND: α-Lipoic acid (α-LA) has been studied as an anticancer agent as well as a therapeutic agent for diabetes and obesity. We performed this study to evaluate the anticancer effects and mechanisms of α-LA in a lung cancer cell line, A549. MATERIALS AND METHODS: α-LA-induced apoptosis of A549...

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Detalles Bibliográficos
Autores principales: Kim, Jong In, Cho, Sung-Rae, Lee, Chang Min, Park, Eok-Sung, Kim, Ki Nyun, Kim, Hyung Chul, Lee, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Thoracic and Cardiovascular Surgery 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283777/
https://www.ncbi.nlm.nih.gov/pubmed/22363901
http://dx.doi.org/10.5090/kjtcs.2012.45.1.1