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DNA Replication Fading As Proliferating Cells Advance in Their Commitment to Terminal Differentiation

Terminal differentiation is the process by which cycling cells stop proliferating to start new specific functions. It involves dramatic changes in chromatin organization as well as gene expression. In the present report we used cell flow cytometry and genome wide DNA combing to investigate DNA repli...

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Detalles Bibliográficos
Autores principales: Estefanía, Monturus Ma., Ganier, Olivier, Hernández, Pablo, Schvartzman, Jorge B., Mechali, Marcel, Krimer, Dora B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283920/
https://www.ncbi.nlm.nih.gov/pubmed/22359734
http://dx.doi.org/10.1038/srep00279