Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores

Importin-β is the main vector for interphase nuclear protein import and plays roles after nuclear envelope breakdown. Here we show that importin-β regulates multiple aspects of mitosis via distinct domains that interact with different classes of proteins in human cells. The C-terminal region (which...

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Detalles Bibliográficos
Autores principales: Roscioli, Emanuele, Di Francesco, Laura, Bolognesi, Alessio, Giubettini, Maria, Orlando, Serena, Harel, Amnon, Schininà, Maria Eugenia, Lavia, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283988/
https://www.ncbi.nlm.nih.gov/pubmed/22331847
http://dx.doi.org/10.1083/jcb.201109104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283988/
https://www.ncbi.nlm.nih.gov/pubmed/22331847
http://dx.doi.org/10.1083/jcb.201109104

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