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Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores
Importin-β is the main vector for interphase nuclear protein import and plays roles after nuclear envelope breakdown. Here we show that importin-β regulates multiple aspects of mitosis via distinct domains that interact with different classes of proteins in human cells. The C-terminal region (which...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283988/ https://www.ncbi.nlm.nih.gov/pubmed/22331847 http://dx.doi.org/10.1083/jcb.201109104 |