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Structure–function mapping of a heptameric module in the nuclear pore complex

The nuclear pore complex (NPC) is a multiprotein assembly that serves as the sole mediator of nucleocytoplasmic exchange in eukaryotic cells. In this paper, we use an integrative approach to determine the structure of an essential component of the yeast NPC, the ∼600-kD heptameric Nup84 complex, to...

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Detalles Bibliográficos
Autores principales: Fernandez-Martinez, Javier, Phillips, Jeremy, Sekedat, Matthew D., Diaz-Avalos, Ruben, Velazquez-Muriel, Javier, Franke, Josef D., Williams, Rosemary, Stokes, David L., Chait, Brian T., Sali, Andrej, Rout, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283990/
https://www.ncbi.nlm.nih.gov/pubmed/22331846
http://dx.doi.org/10.1083/jcb.201109008