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Structure–function mapping of a heptameric module in the nuclear pore complex
The nuclear pore complex (NPC) is a multiprotein assembly that serves as the sole mediator of nucleocytoplasmic exchange in eukaryotic cells. In this paper, we use an integrative approach to determine the structure of an essential component of the yeast NPC, the ∼600-kD heptameric Nup84 complex, to...
Autores principales: | Fernandez-Martinez, Javier, Phillips, Jeremy, Sekedat, Matthew D., Diaz-Avalos, Ruben, Velazquez-Muriel, Javier, Franke, Josef D., Williams, Rosemary, Stokes, David L., Chait, Brian T., Sali, Andrej, Rout, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283990/ https://www.ncbi.nlm.nih.gov/pubmed/22331846 http://dx.doi.org/10.1083/jcb.201109008 |
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