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Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction

The function of the essential checkpoint kinases Bub1 and BubR1 requires their recruitment to mitotic kinetochores. Kinetochore recruitment of Bub1 and BubR1 is proposed to rely on the interaction of the tetratricopeptide repeats (TPRs) of Bub1 and BubR1 with two KI motifs in the outer kinetochore p...

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Detalles Bibliográficos
Autores principales: Krenn, Veronica, Wehenkel, Annemarie, Li, Xiaozheng, Santaguida, Stefano, Musacchio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283998/
https://www.ncbi.nlm.nih.gov/pubmed/22331848
http://dx.doi.org/10.1083/jcb.201110013