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Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction
The function of the essential checkpoint kinases Bub1 and BubR1 requires their recruitment to mitotic kinetochores. Kinetochore recruitment of Bub1 and BubR1 is proposed to rely on the interaction of the tetratricopeptide repeats (TPRs) of Bub1 and BubR1 with two KI motifs in the outer kinetochore p...
Autores principales: | Krenn, Veronica, Wehenkel, Annemarie, Li, Xiaozheng, Santaguida, Stefano, Musacchio, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283998/ https://www.ncbi.nlm.nih.gov/pubmed/22331848 http://dx.doi.org/10.1083/jcb.201110013 |
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