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Comparative metabolism of benzo[a]pyrene by human keratinocytes infected with high-risk human papillomavirus types 16 and 18 as episomal or integrated genomes

BACKGROUND: Infection with human papillomavirus (HPV) is a critical factor in the development of cervical cancer. Smoking is an additional risk factor. Tobacco smoke carcinogens, such as benzo[a]pyrene (B[a]P), and their cytochrome P450-related metabolites are present in significantly higher levels...

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Detalles Bibliográficos
Autores principales: Trushin, Neil, Alam, Samina, El-Bayoumy, Karam, Krzeminski, Jacek, Amin, Shantu G., Gullett, Jenny, Meyers, Craig, Prokopczyk, Bogdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284083/
https://www.ncbi.nlm.nih.gov/pubmed/22368516
http://dx.doi.org/10.4103/1477-3163.92309