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Comparative metabolism of benzo[a]pyrene by human keratinocytes infected with high-risk human papillomavirus types 16 and 18 as episomal or integrated genomes
BACKGROUND: Infection with human papillomavirus (HPV) is a critical factor in the development of cervical cancer. Smoking is an additional risk factor. Tobacco smoke carcinogens, such as benzo[a]pyrene (B[a]P), and their cytochrome P450-related metabolites are present in significantly higher levels...
Autores principales: | Trushin, Neil, Alam, Samina, El-Bayoumy, Karam, Krzeminski, Jacek, Amin, Shantu G., Gullett, Jenny, Meyers, Craig, Prokopczyk, Bogdan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284083/ https://www.ncbi.nlm.nih.gov/pubmed/22368516 http://dx.doi.org/10.4103/1477-3163.92309 |
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