The Effect of Preconception Paternal Alcohol Exposure on Epigenetic Remodeling of the H19 and Rasgrf1 Imprinting Control Regions in Mouse Offspring

Imprinted loci play a critical role in fetal development. Their expression is often regulated by CCCTC-binding factor (CTCF) protein binding at imprinting control regions (ICRs). Prenatal alcohol exposure has been shown to reduce global DNA methylation in the developing mouse fetus. This study explo...

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Detalles Bibliográficos
Autores principales: Knezovich, Jaysen Gregory, Ramsay, Michèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284254/
https://www.ncbi.nlm.nih.gov/pubmed/22371710
http://dx.doi.org/10.3389/fgene.2012.00010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284254/
https://www.ncbi.nlm.nih.gov/pubmed/22371710
http://dx.doi.org/10.3389/fgene.2012.00010

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