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Drug-Drug Interaction Analysis of Pyronaridine/Artesunate and Ritonavir in Healthy Volunteers

A multiple dose, parallel group study was conducted to assess for a drug-drug interaction between the pyronaridine/artesunate (PA) combination antimalarial and ritonavir. Thirty-four healthy adults were randomized (1:1) to receive PA for 3 days or PA with ritonavir (100 mg twice daily for 17 days, P...

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Detalles Bibliográficos
Autores principales: Morris, Carrie A., Lopez-Lazaro, Luis, Jung, Donald, Methaneethorn, Janthima, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Pokorny, Rolf, Shin, Chang-Sik, Fleckenstein, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284369/
https://www.ncbi.nlm.nih.gov/pubmed/22403324
http://dx.doi.org/10.4269/ajtmh.2012.11-0558