Cargando…

Brain-derived neurotrophic factor receptor TrkB exists as a preformed dimer in living cells

BACKGROUND: Neurotrophins (NTs) and their receptors play crucial roles in the development, functions and maintenance of nervous systems. It is widely believed that NT-induced dimerization of the receptors initiates the transmembrane signaling. However, it is still controversial whether the receptor...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Jianying, Maruyama, Ichiro N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284413/
https://www.ncbi.nlm.nih.gov/pubmed/22269274
http://dx.doi.org/10.1186/1750-2187-7-2