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Brain-derived neurotrophic factor receptor TrkB exists as a preformed dimer in living cells
BACKGROUND: Neurotrophins (NTs) and their receptors play crucial roles in the development, functions and maintenance of nervous systems. It is widely believed that NT-induced dimerization of the receptors initiates the transmembrane signaling. However, it is still controversial whether the receptor...
Autores principales: | Shen, Jianying, Maruyama, Ichiro N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284413/ https://www.ncbi.nlm.nih.gov/pubmed/22269274 http://dx.doi.org/10.1186/1750-2187-7-2 |
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