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Decreased defluorination using the novel beta-cell imaging agent [(18)F]FE-DTBZ-d4 in pigs examined by PET

BACKGROUND: Fluorine-18 dihydrotetrabenazine [DTBZ] analogues, which selectively target the vesicular monoamine transporter 2 [VMAT2], have been extensively studied for in vivo quantification of beta cell mass by positron-emission tomography [PET]. This study describes a novel deuterated radioligand...

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Detalles Bibliográficos
Autores principales: Jahan, Mahabuba, Eriksson, Olof, Johnström, Peter, Korsgren, Olle, Sundin, Anders, Johansson, Lars, Halldin, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284452/
https://www.ncbi.nlm.nih.gov/pubmed/22214308
http://dx.doi.org/10.1186/2191-219X-1-33