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Decreased defluorination using the novel beta-cell imaging agent [(18)F]FE-DTBZ-d4 in pigs examined by PET
BACKGROUND: Fluorine-18 dihydrotetrabenazine [DTBZ] analogues, which selectively target the vesicular monoamine transporter 2 [VMAT2], have been extensively studied for in vivo quantification of beta cell mass by positron-emission tomography [PET]. This study describes a novel deuterated radioligand...
Autores principales: | Jahan, Mahabuba, Eriksson, Olof, Johnström, Peter, Korsgren, Olle, Sundin, Anders, Johansson, Lars, Halldin, Christer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284452/ https://www.ncbi.nlm.nih.gov/pubmed/22214308 http://dx.doi.org/10.1186/2191-219X-1-33 |
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