The Max b-HLH-LZ Can Transduce into Cells and Inhibit c-Myc Transcriptional Activities

The inhibition of the functions of c-Myc (endogenous and oncogenic) was recently shown to provide a spectacular therapeutic index in cancer mouse models, with complete tumor regression and minimal side-effects in normal tissues. This was achieved by the systemic and conditional expression of omomyc,...

Descripción completa

Detalles Bibliográficos
Autores principales: Montagne, Martin, Beaudoin, Nicolas, Fortin, David, Lavoie, Christine L., Klinck, Roscoe, Lavigne, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284561/
https://www.ncbi.nlm.nih.gov/pubmed/22384171
http://dx.doi.org/10.1371/journal.pone.0032172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284561/
https://www.ncbi.nlm.nih.gov/pubmed/22384171
http://dx.doi.org/10.1371/journal.pone.0032172

Ejemplares similares