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The Max b-HLH-LZ Can Transduce into Cells and Inhibit c-Myc Transcriptional Activities
The inhibition of the functions of c-Myc (endogenous and oncogenic) was recently shown to provide a spectacular therapeutic index in cancer mouse models, with complete tumor regression and minimal side-effects in normal tissues. This was achieved by the systemic and conditional expression of omomyc,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284561/ https://www.ncbi.nlm.nih.gov/pubmed/22384171 http://dx.doi.org/10.1371/journal.pone.0032172 |