Arsenic Trioxide Exerts Antimyeloma Effects by Inhibiting Activity in the Cytoplasmic Substrates of Histone Deacetylase 6

Arsenic trioxide (As(2)O(3)) has shown remarkable efficacy for the treatment of multiple myeloma (MM). Histone deacetylases (HDAC) play an important role in the control of gene expression, and their dysregulation has been linked to myeloma. Especially, HDAC6, a unique cytoplasmic member of class II,...

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Detalles Bibliográficos
Autores principales: Qu, Xiaoyan, Du, Juan, Zhang, Chunyang, Fu, Weijun, Xi, Hao, Zou, Jianfeng, Hou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284565/
https://www.ncbi.nlm.nih.gov/pubmed/22384180
http://dx.doi.org/10.1371/journal.pone.0032215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284565/
https://www.ncbi.nlm.nih.gov/pubmed/22384180
http://dx.doi.org/10.1371/journal.pone.0032215

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