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Plasmalemmal Na(+)/Ca(2+) exchanger modulates Ca(2+)-dependent exocytotic release of glutamate from rat cortical astrocytes

Astroglial excitability operates through increases in Ca(2+)(cyt) (cytosolic Ca(2+)), which can lead to glutamatergic gliotransmission. In parallel fluctuations in astrocytic Na(+)(cyt) (cytosolic Na(+)) control metabolic neuronal-glial signalling, most notably through stimulation of lactate product...

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Detalles Bibliográficos
Autores principales: Reyes, Reno C, Verkhratsky, Alexei, Parpura, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284767/
https://www.ncbi.nlm.nih.gov/pubmed/22268447
http://dx.doi.org/10.1042/AN20110059