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Chronic excitotoxin-induced axon degeneration in a compartmented neuronal culture model

Glutamate excitotoxicity is a major pathogenic process implicated in many neurodegenerative conditions, including AD (Alzheimer's disease) and following traumatic brain injury. Occurring predominantly from over-stimulation of ionotropic glutamate receptors located along dendrites, excitotoxic a...

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Detalles Bibliográficos
Autores principales: Hosie, Katherine A, King, Anna E, Blizzard, Catherine A, Vickers, James C, Dickson, Tracey C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284768/
https://www.ncbi.nlm.nih.gov/pubmed/22356284
http://dx.doi.org/10.1042/AN20110031