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A network flow approach to predict drug targets from microarray data, disease genes and interactome network - case study on prostate cancer

BACKGROUND: Systematic approach for drug discovery is an emerging discipline in systems biology research area. It aims at integrating interaction data and experimental data to elucidate diseases and also raises new issues in drug discovery for cancer treatment. However, drug target discovery is stil...

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Detalles Bibliográficos
Autores principales: Yeh, Shih-Heng, Yeh, Hsiang-Yuan, Soo, Von-Wun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285036/
https://www.ncbi.nlm.nih.gov/pubmed/22239822
http://dx.doi.org/10.1186/2043-9113-2-1