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Structures of (5′S)-8,5′-Cyclo-2′-deoxyguanosine Mismatched with dA or dT

[Image: see text] Diastereomeric 8,5′-cyclopurine 2′-deoxynucleosides, containing a covalent bond between the deoxyribose and the purine base, are induced in DNA by ionizing radiation. They are suspected to play a role in the etiology of neurodegeneration in xeroderma pigmentosum patients. If not re...

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Detalles Bibliográficos
Autores principales: Huang, Hai, Das, Rajat S., Basu, Ashis K., Stone, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285119/
https://www.ncbi.nlm.nih.gov/pubmed/22309170
http://dx.doi.org/10.1021/tx2005053