Cargando…

Selection of Monoclonal Antibodies Against 6-oxo-M(1)dG and Their Use in an LC-MS/MS Assay for the Presence of 6-oxo-M(1)dG in Vivo

[Image: see text] Oxidative stress triggers DNA and lipid peroxidation, leading to the formation of electrophiles that react with DNA to form adducts. A product of this pathway, (3-(2′-deoxy-β-d-erythro-pentofuranosyl)-pyrimido[1,2-α]purine-10(3H)-one), or M(1)dG, is mutagenic in bacterial and mamma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Akingbade, Dapo, Kingsley, Philip J., Shuck, Sarah C., Cooper, Tracy, Carnahan, Robert, Szekely, Jozef, Marnett, Lawrence J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2012
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285145/ https://www.ncbi.nlm.nih.gov/pubmed/22211372 http://dx.doi.org/10.1021/tx200494h

Ejemplares similares

(Fapy)dG in the Shadow of (OXO)dG—A Theoretical Study of Clustered DNA Lesions
por: Karwowski, Bolesław T.
Publicado: (2023)

The peroxidation-derived DNA adduct, 6-oxo-M(1)dG, is a strong block to replication by human DNA polymerase η
por: Richie-Jannetta, Robyn, et al.
Publicado: (2023)

The Electronic Property Differences between dA::dG and dA::dG(oxo). A Theoretical Approach
por: Karwowski, Boleslaw T.
Publicado: (2020)

Relationship of plasma MBP and 8-oxo-dG with brain damage in preterm
por: Zhao, Yuwei, et al.
Publicado: (2022)

Serum 8-Oxo-dG as a Predictor of Sensitivity and Outcome of Radiotherapy and Chemotherapy of Upper Gastrointestinal Tumours
por: Pour Khavari, Ali, et al.
Publicado: (2018)

Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M(1)dG
por: Cline, Susan D., et al.
Publicado: (2010)

Oxidative stress increases M(1)dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA
por: Wauchope, Orrette R, et al.
Publicado: (2018)

Aptamer-based colorimetric detection of the DNA damage marker 8-oxo-dG using cysteamine-stabilised gold nanoparticles
por: Sakonsinsiri, Chadamas, et al.
Publicado: (2022)

The Influence of Spirodi(Iminohydantoin) on Charge Transfer through ds-DNA Containing 8-OXO-dG: A Theoretical Approach
por: Karwowski, Boleslaw T.
Publicado: (2023)

Oxidative Stress and DNA Damage in Human Gastric Carcinoma: 8-Oxo-7′8-dihydro-2′-deoxyguanosine (8-oxo-dG) as a Possible Tumor Marker
por: Borrego, Silvia, et al.
Publicado: (2013)

The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa
por: Maddukuri, Leena, et al.
Publicado: (2014)

Development of Low-Cost AuNP-Based Aptasensors with Truncated Aptamer for Highly Sensitive Detection of 8-Oxo-dG in Urine
por: Matulakul, Piyaporn, et al.
Publicado: (2020)

Differential Expression Profiles of Oxidative Stress Levels, 8-oxo-dG and 4-HNE, in Barrett’s Esophagus Compared to Esophageal Adenocarcinoma
por: O’Farrell, Naoimh J., et al.
Publicado: (2019)

Effects of Tomato Juice Intake on Salivary 8-Oxo-dG Levels as Oxidative Stress Biomarker after Extensive Physical Exercise
por: Pour Khavari, Ali, et al.
Publicado: (2020)

Synthesis of novel poly(dG)–poly(dG)–poly(dC) triplex structure by Klenow exo(−) fragment of DNA polymerase I
por: Kotlyar, Alexander, et al.
Publicado: (2005)

Formation of a N(2)-dG:N(2)-dG Carbinolamine DNA Cross-link by the trans-4-Hydroxynonenal-Derived (6S,8R,11S) 1,N(2)-dG Adduct
por: Huang, Hai, et al.
Publicado: (2011)

Dynamic Basis for dG•dT misincorporation via tautomerization and ionization
por: Kimsey, Isaac J., et al.
Publicado: (2018)

Restriction and modification of deoxyarchaeosine (dG(+))-containing phage 9 g DNA
por: Tsai, Rebecca, et al.
Publicado: (2017)

RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications
por: Mutso, Margit, et al.
Publicado: (2015)

Development of an LC−MS/MS method for determination of 2-oxo-clopidogrel in human plasma
por: Li, Yu-Han, et al.
Publicado: (2015)

Telomerase-targeting compounds Imetelstat and 6-thio-dG act synergistically with chemotherapy in high-risk neuroblastoma models
por: Fischer-Mertens, Janina, et al.
Publicado: (2022)

One-year follow-up of clinical, metabolic and oxidative stress profile of morbid obese patients after laparoscopic sleeve gastrectomy. 8-oxo-dG as a clinical marker
por: Monzo-Beltran, Lidia, et al.
Publicado: (2017)

Value of the 8-oxodG/dG ratio in chronic liver inflammation of patients with hepatocellular carcinoma
por: Li, Pengcheng, et al.
Publicado: (2016)

DG' Presentation
por: Heuer, Rolf
Publicado: (2015)

DG Euronews
Publicado: (1997)

Presentation of the DG
por: CERN. Geneva
Publicado: (2010)

Speach of the DG
por: Llewellyn Smith, Christopher Hubert
Publicado: (1997)

DG's Presentation
por: Gianotti, Fabiola
Publicado: (2016)

Structural basis for 2′-deoxyguanosine recognition by the 2′-dG-II class of riboswitches
por: Matyjasik, Michal M, et al.
Publicado: (2019)

In vitro synthesis of uniform poly(dG)–poly(dC) by Klenow exo(−) fragment of polymerase I
por: Kotlyar, Alexander B., et al.
Publicado: (2005)

Dynamics of the excited-state hydrogen transfer in a (dG)·(dC) homopolymer: intrinsic photostability of DNA
por: Francés-Monerris, Antonio, et al.
Publicado: (2018)

DG's staff talk
por: CERN. Geneva. Experimental Physics (EP) division
Publicado: (2001)

DG's Staff meeting
por: CERN. Geneva. Experimental Physics (EP) division
Publicado: (2000)

Introduction to CERN by the DG
por: Heuer, Rolf
Publicado: (2014)

DG's talk to Staff
por: CERN. Geneva
Publicado: (2011)

DG's Staff Meeting
por: Rubbia, Carlo
Publicado: (1990)

DG Staff Meeting
por: Rubbia, Carlo
Publicado: (1989)

DG-Computing policy
por: Krige, A
Publicado: (1986)

Message from the DG
por: Aymar, R
Publicado: (2008)

Message from the DG
por: Rolf Heuer
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_hju5ve6seb2k3438brdgv0l82q