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Thioredoxin Glutathione Reductase as a Novel Drug Target: Evidence from Schistosoma japonicum
BACKGROUND: Schistosomiasis remains a major public health concern affecting billions of people around the world. Currently, praziquantel is the only drug of choice for treatment of human schistosomiasis. The emergence of drug resistance to praziquantel in schistosomes makes the development of novel...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285170/ https://www.ncbi.nlm.nih.gov/pubmed/22384025 http://dx.doi.org/10.1371/journal.pone.0031456 |