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Novel cis-Regulatory Modules Control Expression of the Hairy and Enhancer of Split-1 (HES1) Transcription Factor in Myoblasts
The expression profile of a gene is controlled by DNA sequences called cis-regulatory modules (CRMs). CRMs can function over large genomic distances and can be located many kilobases away from their target promoters. hes1 is a key developmental gene that is overexpressed in certain cancers and is a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285341/ https://www.ncbi.nlm.nih.gov/pubmed/22167192 http://dx.doi.org/10.1074/jbc.M111.286484 |