Characterization of Spindle Checkpoint Kinase Mps1 Reveals Domain with Functional and Structural Similarities to Tetratricopeptide Repeat Motifs of Bub1 and BubR1 Checkpoint Kinases

Kinetochore targeting of the mitotic kinases Bub1, BubR1, and Mps1 has been implicated in efficient execution of their functions in the spindle checkpoint, the self-monitoring system of the eukaryotic cell cycle that ensures chromosome segregation occurs with high fidelity. In all three kinases, kin...

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Detalles Bibliográficos
Autores principales: Lee, Semin, Thebault, Philippe, Freschi, Luca, Beaufils, Sylvie, Blundell, Tom L., Landry, Christian R., Bolanos-Garcia, Victor M., Elowe, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
DNA and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285366/
https://www.ncbi.nlm.nih.gov/pubmed/22187426
http://dx.doi.org/10.1074/jbc.M111.307355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285366/
https://www.ncbi.nlm.nih.gov/pubmed/22187426
http://dx.doi.org/10.1074/jbc.M111.307355

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