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Structural Consensus among Antibodies Defines the Antigen Binding Site

The Complementarity Determining Regions (CDRs) of antibodies are assumed to account for the antigen recognition and binding and thus to contain also the antigen binding site. CDRs are typically discerned by searching for regions that are most different, in sequence or in structure, between different...

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Detalles Bibliográficos
Autores principales: Kunik, Vered, Peters, Bjoern, Ofran, Yanay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285572/
https://www.ncbi.nlm.nih.gov/pubmed/22383868
http://dx.doi.org/10.1371/journal.pcbi.1002388