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Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

Pathway analysis has become the first choice for gaining insight into the underlying biology of differentially expressed genes and proteins, as it reduces complexity and has increased explanatory power. We discuss the evolution of knowledge base–driven pathway analysis over its first decade, distinc...

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Detalles Bibliográficos
Autores principales: Khatri, Purvesh, Sirota, Marina, Butte, Atul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285573/
https://www.ncbi.nlm.nih.gov/pubmed/22383865
http://dx.doi.org/10.1371/journal.pcbi.1002375