A Cell-based Computational Modeling Approach for Developing Site-Directed Molecular Probes

Modeling the local absorption and retention patterns of membrane-permeant small molecules in a cellular context could facilitate development of site-directed chemical agents for bioimaging or therapeutic applications. Here, we present an integrative approach to this problem, combining in silico comp...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Jing-yu, Zheng, Nan, Mane, Gerta, Min, Kyoung Ah, Hinestroza, Juan P., Zhu, Huaning, Stringer, Kathleen A., Rosania, Gus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285574/
https://www.ncbi.nlm.nih.gov/pubmed/22383866
http://dx.doi.org/10.1371/journal.pcbi.1002378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285574/
https://www.ncbi.nlm.nih.gov/pubmed/22383866
http://dx.doi.org/10.1371/journal.pcbi.1002378

Ejemplares similares