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The Caenorhabditis elegans Eph Receptor Activates NCK and N-WASP, and Inhibits Ena/VASP to Regulate Growth Cone Dynamics during Axon Guidance

The Eph receptor tyrosine kinases (RTKs) are regulators of cell migration and axon guidance. However, our understanding of the molecular mechanisms by which Eph RTKs regulate these processes is still incomplete. To understand how Eph receptors regulate axon guidance in Caenorhabditis elegans, we scr...

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Detalles Bibliográficos
Autores principales: Mohamed, Ahmed M., Boudreau, Jeffrey R., Yu, Fabian P. S., Liu, Jun, Chin-Sang, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285579/
https://www.ncbi.nlm.nih.gov/pubmed/22383893
http://dx.doi.org/10.1371/journal.pgen.1002513