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Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes

Metabolic Syndrome (MetS) is highly prevalent and has considerable public health impact, but its underlying genetic factors remain elusive. To identify gene networks involved in MetS, we conducted whole-genome expression and genotype profiling on abdominal (ABD) and gluteal (GLU) adipose tissue, and...

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Detalles Bibliográficos
Autores principales: Min, Josine L., Nicholson, George, Halgrimsdottir, Ingileif, Almstrup, Kristian, Petri, Andreas, Barrett, Amy, Travers, Mary, Rayner, Nigel W., Mägi, Reedik, Pettersson, Fredrik H., Broxholme, John, Neville, Matt J., Wills, Quin F., Cheeseman, Jane, Allen, Maxine, Holmes, Chris C., Spector, Tim D., Fleckner, Jan, McCarthy, Mark I., Karpe, Fredrik, Lindgren, Cecilia M., Zondervan, Krina T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285582/
https://www.ncbi.nlm.nih.gov/pubmed/22383892
http://dx.doi.org/10.1371/journal.pgen.1002505