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The Legionella pneumophila Effector VipA Is an Actin Nucleator That Alters Host Cell Organelle Trafficking

Legionella pneumophila, the causative agent of Legionnaires' disease, invades and replicates within macrophages and protozoan cells inside a vacuole. The type IVB Icm/Dot secretion system is necessary for the translocation of effector proteins that modulate vesicle trafficking pathways in the h...

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Detalles Bibliográficos
Autores principales: Franco, Irina Saraiva, Shohdy, Nadim, Shuman, Howard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285593/
https://www.ncbi.nlm.nih.gov/pubmed/22383880
http://dx.doi.org/10.1371/journal.ppat.1002546