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Nonequivalence of Classical MHC Class I Loci in Ability to Direct Effective Antiviral Immunity

Structural diversity in the peptide binding sites of the redundant classical MHC antigen presenting molecules is strongly selected in humans and mice. Although the encoded antigen presenting molecules overlap in antigen presenting function, differences in polymorphism at the MHC I A, B and C loci in...

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Detalles Bibliográficos
Autores principales: Pavelko, Kevin D., Mendez-Fernandez, Yanice, Bell, Michael P., Hansen, Michael J., Johnson, Aaron J., David, Chella S., Rodriguez, Moses, Pease, Larry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285594/
https://www.ncbi.nlm.nih.gov/pubmed/22383876
http://dx.doi.org/10.1371/journal.ppat.1002541