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LEM-3 – A LEM Domain Containing Nuclease Involved in the DNA Damage Response in C. elegans
The small nematode Caenorhabditis elegans displays a spectrum of DNA damage responses similar to humans. In order to identify new DNA damage response genes, we isolated in a forward genetic screen 14 new mutations conferring hypersensitivity to ionizing radiation. We present here our characterizatio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285610/ https://www.ncbi.nlm.nih.gov/pubmed/22383942 http://dx.doi.org/10.1371/journal.pone.0024555 |