Cargando…

LEM-3 – A LEM Domain Containing Nuclease Involved in the DNA Damage Response in C. elegans

The small nematode Caenorhabditis elegans displays a spectrum of DNA damage responses similar to humans. In order to identify new DNA damage response genes, we isolated in a forward genetic screen 14 new mutations conferring hypersensitivity to ionizing radiation. We present here our characterizatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Dittrich, Christina M., Kratz, Katja, Sendoel, Ataman, Gruenbaum, Yosef, Jiricny, Josef, Hengartner, Michael O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285610/
https://www.ncbi.nlm.nih.gov/pubmed/22383942
http://dx.doi.org/10.1371/journal.pone.0024555

Ejemplares similares