Simukunin from the Salivary Glands of the Black Fly Simulium vittatum Inhibits Enzymes That Regulate Clotting and Inflammatory Responses

BACKGROUND: Black flies (Diptera: Simuliidae) feed on blood, and are important vectors of Onchocerca volvulus, the etiolytic agent of River Blindness. Blood feeding depends on pharmacological properties of saliva, including anticoagulation, but the molecules responsible for this activity have not be...

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Detalles Bibliográficos
Autores principales: Tsujimoto, Hitoshi, Kotsyfakis, Michail, Francischetti, Ivo M. B., Eum, Jai Hoon, Strand, Michael R., Champagne, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285612/
https://www.ncbi.nlm.nih.gov/pubmed/22383955
http://dx.doi.org/10.1371/journal.pone.0029964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285612/
https://www.ncbi.nlm.nih.gov/pubmed/22383955
http://dx.doi.org/10.1371/journal.pone.0029964

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