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Genetic Abolishment of Hepatocyte Proliferation Activates Hepatic Stem Cells
Quiescent hepatic stem cells (HSCs) can be activated when hepatocyte proliferation is compromised. Chemical injury rodent models have been widely used to study the localization, biomarkers, and signaling pathways in HSCs, but these models usually exhibit severe promiscuous toxicity and fail to disti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285627/ https://www.ncbi.nlm.nih.gov/pubmed/22384083 http://dx.doi.org/10.1371/journal.pone.0031846 |