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Genetic Abolishment of Hepatocyte Proliferation Activates Hepatic Stem Cells

Quiescent hepatic stem cells (HSCs) can be activated when hepatocyte proliferation is compromised. Chemical injury rodent models have been widely used to study the localization, biomarkers, and signaling pathways in HSCs, but these models usually exhibit severe promiscuous toxicity and fail to disti...

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Detalles Bibliográficos
Autores principales: Endo, Yoko, Zhang, Mingjun, Yamaji, Sachie, Cang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285627/
https://www.ncbi.nlm.nih.gov/pubmed/22384083
http://dx.doi.org/10.1371/journal.pone.0031846