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A Bistable Model of Cell Polarity

Ultrasensitivity, as described by Goldbeter and Koshland, has been considered for a long time as a way to realize bistable switches in biological systems. It is not as well recognized that when ultrasensitivity and reinforcing feedback loops are present in a spatially distributed system such as the...

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Detalles Bibliográficos
Autores principales: Semplice, Matteo, Veglio, Andrea, Naldi, Giovanni, Serini, Guido, Gamba, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285628/
https://www.ncbi.nlm.nih.gov/pubmed/22383986
http://dx.doi.org/10.1371/journal.pone.0030977