Disparate Impact of Butyroyloxymethyl Diethylphosphate (AN-7), a Histone Deacetylase Inhibitor, and Doxorubicin in Mice Bearing a Mammary Tumor

The histone deacetylase inhibitor (HDACI) butyroyloxymethyl diethylphosphate (AN-7) synergizes the cytotoxic effect of doxorubicin (Dox) and anti-HER2 on mammary carcinoma cells while protecting normal cells against their insults. This study investigated the concomitant changes occurring in heart ti...

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Detalles Bibliográficos
Autores principales: Tarasenko, Nataly, Cutts, Suzanne M., Phillips, Don R., Inbal, Aida, Nudelman, Abraham, Kessler-Icekson, Gania, Rephaeli, Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285631/
https://www.ncbi.nlm.nih.gov/pubmed/22384017
http://dx.doi.org/10.1371/journal.pone.0031393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285631/
https://www.ncbi.nlm.nih.gov/pubmed/22384017
http://dx.doi.org/10.1371/journal.pone.0031393

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