Genetic Ablation of Pannexin1 Protects Retinal Neurons from Ischemic Injury

Pannexin1 (Panx1) forms large nonselective membrane channel that is implicated in paracrine and inflammatory signaling. In vitro experiments suggested that Panx1 could play a key role in ischemic death of hippocampal neurons. Since retinal ganglion cells (RGCs) express high levels of Panx1 and are s...

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Detalles Bibliográficos
Autores principales: Dvoriantchikova, Galina, Ivanov, Dmitry, Barakat, David, Grinberg, Alexander, Wen, Rong, Slepak, Vladlen Z., Shestopalov, Valery I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285635/
https://www.ncbi.nlm.nih.gov/pubmed/22384122
http://dx.doi.org/10.1371/journal.pone.0031991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285635/
https://www.ncbi.nlm.nih.gov/pubmed/22384122
http://dx.doi.org/10.1371/journal.pone.0031991

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