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GSK3 Inhibitor-BIO Regulates Proliferation of Immortalized Pancreatic Mesenchymal Stem Cells (iPMSCs)

BACKGROUND: The small molecule 6-bromoindirubin-30-oxime (BIO), a glycogen synthase kinase 3 (GSK3) inhibitor, is a pharmacological agent known to maintain self-renewal in human and mouse embryonic stem cells (ESCs). However, the precise role of GSK3 in immortalized pancreatic mesenchymal stem cells...

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Detalles Bibliográficos
Autores principales: Cao, Hui, Chu, Yuankui, Lv, Xiao, Qiu, Pubin, Liu, Chao, Zhang, Huiru, Li, Dan, Peng, Sha, Dou, Zhongying, Hua, Jinlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285662/
https://www.ncbi.nlm.nih.gov/pubmed/22384031
http://dx.doi.org/10.1371/journal.pone.0031502