Pro-Inflammatory wnt5a and Anti-Inflammatory sFRP5 Are Differentially Regulated by Nutritional Factors in Obese Human Subjects

BACKGROUND: Obesity is associated with macrophage infiltration of adipose tissue. These inflammatory cells affect adipocytes not only by classical cytokines but also by the secreted glycopeptide wnt5a. Healthy adipocytes are able to release the wnt5a inhibitor sFRP5. This protective effect, however,...

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Detalles Bibliográficos
Autores principales: Schulte, Dominik M., Müller, Nike, Neumann, Katrin, Oberhäuser, Frank, Faust, Michael, Güdelhöfer, Heike, Brandt, Burkhard, Krone, Wilhelm, Laudes, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285685/
https://www.ncbi.nlm.nih.gov/pubmed/22384249
http://dx.doi.org/10.1371/journal.pone.0032437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285685/
https://www.ncbi.nlm.nih.gov/pubmed/22384249
http://dx.doi.org/10.1371/journal.pone.0032437

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