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Pro-Inflammatory wnt5a and Anti-Inflammatory sFRP5 Are Differentially Regulated by Nutritional Factors in Obese Human Subjects
BACKGROUND: Obesity is associated with macrophage infiltration of adipose tissue. These inflammatory cells affect adipocytes not only by classical cytokines but also by the secreted glycopeptide wnt5a. Healthy adipocytes are able to release the wnt5a inhibitor sFRP5. This protective effect, however,...
Autores principales: | Schulte, Dominik M., Müller, Nike, Neumann, Katrin, Oberhäuser, Frank, Faust, Michael, Güdelhöfer, Heike, Brandt, Burkhard, Krone, Wilhelm, Laudes, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285685/ https://www.ncbi.nlm.nih.gov/pubmed/22384249 http://dx.doi.org/10.1371/journal.pone.0032437 |
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