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Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA
BACKGROUND: Proliferation and migration of vascular smooth muscle cells (VSMCs) play a key role in neointimal formation which leads to restenosis of vein graft in venous bypass. STAT-3 is a transcription factor associated with cell proliferation. We hypothesized that silencing of STAT-3 by siRNA wil...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286375/ https://www.ncbi.nlm.nih.gov/pubmed/22216901 http://dx.doi.org/10.1186/1479-5876-10-2 |