Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA

BACKGROUND: Proliferation and migration of vascular smooth muscle cells (VSMCs) play a key role in neointimal formation which leads to restenosis of vein graft in venous bypass. STAT-3 is a transcription factor associated with cell proliferation. We hypothesized that silencing of STAT-3 by siRNA wil...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jiangbin, Zheng, Jinhua, Ling, Kaitelynne H, Zhao, Keyan, Xie, Zhongshang, Li, Bo, Wang, Tiance, Zhu, Zhicheng, Patel, Amit N, Min, Weiping, Liu, Kexiang, Zheng, Xiufen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286375/
https://www.ncbi.nlm.nih.gov/pubmed/22216901
http://dx.doi.org/10.1186/1479-5876-10-2

Ejemplares similares

Ejemplares similares