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The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2

BACKGROUND: Host cell invasion by the foodborne pathogen Campylobacter jejuni is considered as one of the primary reasons of gut tissue damage, however, mechanisms and key factors involved in this process are widely unclear. It was reported that small Rho GTPases, including Cdc42, are activated and...

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Detalles Bibliográficos
Autores principales: Krause-Gruszczynska, Malgorzata, Boehm, Manja, Rohde, Manfred, Tegtmeyer, Nicole, Takahashi, Seiichiro, Buday, Laszlo, Oyarzabal, Omar A, Backert, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286397/
https://www.ncbi.nlm.nih.gov/pubmed/22204307
http://dx.doi.org/10.1186/1478-811X-9-32